Adderall Side Effects . WARNINGAMPHETAMINES HAVE A HIGH POTENTIAL FOR ABUSE. ADMINISTRATION OF AMPHETAMINES FOR PROLONGED PERIODS OF TIME MAY LEAD TO DRUG DEPENDENCE AND MUST BE AVOIDED. PARTICULAR ATTENTION SHOULD BE PAID TO THE POSSIBILITY OF SUBJECTS OBTAINING AMPHETAMINES FOR NONTHERAPEUTIC USE OR DISTRIBUTION TO OTHERS, AND THE DRUGS SHOULD BE PRESCRIBED OR DISPENSED SPARINGLY. MISUSE OF AMPHETAMINE MAY CAUSE SUDDEN DEATH AND SERIOUS CARDIOVASCULAR ADVERSE EVENTS. ABOVE: FDA black box warning label appears on the manufacturer's wholesale packaging and is the strongest alert the FDA can require. But a skilled clinician should be able to. ABOVE: Psychology Today Diagnosis Dictionary: Amphetamines; last reviewed Jan. Adderall XR is a powerful blend of four amphetamines that includes Dexedrine and Benzedrine. Side effects of these medications include some loss of appetite, weight loss, sleep problems, irritability, tics. They require frequent dosing. The FDA has issued a. Page 1 of 7 Adderall (amphetamine) FDA ALERT Jan. 8, 2. 00. 8. Description. Adderall XR (and Adderall) is a blend of four (4) amphetamines, as shown below. Used For. Attention deficit disorder. Narcolepsy. Depression. Obesity. How Amphetamines Work. When we are stressed or under threat, the central nervous system prepares us for physical action by creating particular physiological changes. Methamphetamine prompts the brain to initiate this . These changes include: The release of adrenalin and other stress hormones. Medscape - Indication-specific dosing for Dexedrine, ProCentra (dextroamphetamine), frequency-based adverse effects, comprehensive interactions, contraindications. Home > Help > Parents/Children > Update on Medications Used in The Treatment of ADHD. By Patricia Quinn, M.D. Over the last decade, many advances have been made in. Find a comprehensive guide to possible side effects including common and rare side effects when taking Vyvanse (Lisdexamfetamine Dimesylate) for healthcare. Increased heart rate and blood pressure. Redirected blood flow into the muscles and away from the gut. In small doses amphetamines can banish tiredness and make the user feel alert and refreshed. However, the burst of energy comes at a price. A “speed crash” always follows the high and may leave the person feeling nauseous, irritable, depressed and extremely exhausted. Do Not Use If. You have not tried other psychotherapy, have high blood pressure or any form of heart disease, are very nervous or have severe insomnia, have a history of addiction to drugs or alcohol, or have Tourette syndrome. Do not combine with monoamine oxidase inhibitors. Common Side Effects. Dry Mouth. Loss of appetite Headache. Difficulty falling asleep (insomnia)Nervousness including agitation, anxiety and irritability. Addiction. Less Common Side Effects. High blood pressure Rapid pulse rate Tolerance (constant need to raise the dose) Feelings of suspicion and paranoia. Visual hallucinations (seeing things that are not there)Depression. Cocaine craving Dermatoses (infected or diseased skin) Urinary tract infection. Infection or viral infection Elevated ALT enzyme levels in the blood (signaling liver damage)Overdose Side Effects. Amphetamines have been extensively abused. Adderall (Adderall XR) is a prescription medication used to treat attention deficit hyperactivity disorder (ADHD) and narcolepsy in children and adults. Extreme psychological dependence and severe social disability have resulted. Abuse of amphetamines may cause a sudden heart attack even in those with no signs of heart disease. Symptoms of overdose that require immediate medical assistance include: Restlessness. Tremor. Aggression. Hallucinations. Panic states. Hyperreflexia (overactive reflexes, which can include twitching or spasms) Personality changes Symptoms of depression. Seizures or abnormal EEGs. High blood pressure. Rapid heart beat. Swelling of hands/feet/ankles (for example, numbing of the fingertips)Delusions. Sweating. Vomiting. Dehydration. Unexplained muscle pain. Lower abdominal pain. Rhabdomyolysis and kidney damage. Chronic abuse can manifest itself as psychosis, often indistinguishable from schizophrenia. Amphetamine- Induced Anxiety Disorder. The onset of amphetamine- induced anxiety disorder can occur during amphetamine use or withdrawal, according to best- selling psychiatry text, Kaplan and Sadock's Synopsis of Psychiatry citing the American Psychiatric Association's Diagnostic and Statistical Manual of Mental Disorders.“Amphetamine, as with cocaine, can induce symptoms similar to those seen in obsessive disorder, panic disorder, and phobic disorders,” states Synopsis of Psychiatry. Adderall- Induced Psychosis. Induction of schizophrenic- like states in children on prescribed doses of stimulant medications, including Adderall, have been observed, though not as well documented as with amphetamine abusers, according to The Journal of the American Board of Family Medicine in an article entitled, “Adderall- Induced Psychosis in an Adolescent.”Amphetamine- Induced Sexual Dysfunction. The American Psychiatric Association’s Manual of Mental Disorders, Synopsis of Psychiatry states: “High doses and long- term use of amphetamines are associated with erectile disorder and other sexual dysfunctions.”FDA: Links Between ADHD Drugs and Priapism and Sexual Dysfunction. In a 2. 01. 3 drug- safety announcement, the FDA announced that drugs containing methylphenidate must including warnings about the risk of priapism. It's a serious problem. Priapism is a persistent, usually painful, erection that lasts for more than four hours and occurs without sexual stimulation. If the condition is not treated immediately, it can lead to scarring and permanent erectile dysfunction. The safety warning also raised concerns about links between priapism and amphetamine drugs, which include Adderall. ABOVE: U. S. FDA Drug Safety Communication, “FDA warns of rare risk of long- lasting erections in males taking methylphenidate ADHD medications and has approved label changes.” (1. Over time, the body might come to depend on amphetamines just to function normally. The person craves the drug and their psychological dependence makes them panic if access is denied, even temporarily. Some people experience a pattern of “binge crash” characterized by using continuously for several days without sleep, followed by a period of heavy sleeping. If It Doesn't Work. The drug should be stopped gradually. Withdrawal symptoms are psychological and stopping suddenly can cause extreme fatigue and severe, even suicidal, depression in adult patients. Abrupt cessation of Adderall and Adderall XR can cause extreme fatigue and severe, even suicidal, depression in adult patients. ABOVE: The Essential Guide to Psychiatric Drugs—Rev. This is, in my opinion, a very serious mistake,” states Jack M. Gorman, M. D., professor of psychiatry at Columbia University and deputy director of the New York State Psychiatric Institute. It is a very powerful drug that undoubtedly works for ADHD, but there are alternatives with less abuse potential that should be tried first.”2. Sudden Deaths Linked to Adderall XRas reported by Associated Press (February 1. Adderall XR, a widely used drug for attention deficit hyperactivity disorder, was pulled off the market in Canada after regulators linked the drug to 2. Fourteen of the deaths and two of the 1. The adverse reactions were not associated with overdose, misuse or abuse of Adderall XR, Canadian regulators said. The U. S. Food and Drug Administration issued a public health advisory to alert providers to the withdrawal. But the agency also said it had evaluated the same reports as Canadian regulators and did not think the data warranted pulling the drug from the U. S. NY Times: Children's A. D. D. Drugs Don't Work Long- Term. The NY Times, in an op- ed article by L. Alan Sroufe, a professor emeritus of psychology at the University of Minnesota's Institute of Child Development, stated the following: “Attention- deficit drugs increase concentration in the short term, which is why they work so well for college students cramming for exams. But when given to children over long periods of time, they neither improve school achievement nor reduce behavior problems. The drugs can also have serious side effects.. Many parents who take their children off the drugs find that behavior worsens, which most likely confirms their belief that the drugs work. But the behavior worsens because the children's bodies have become adapted . Adults may have similar reactions if they suddenly cut back on coffee, or stop smoking.”Parents might want to consider another approach. ABOVE: L. Alan Sroufe, “Ritalin Gone Wrong: Children's A. D. D. Drugs Don't Work Long- Term,” New York Times, pg SR1, NY ed, 1/2.
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